How are neoplasms primarily classified in pathology?

In pathology, neoplasms are primarily classified by their tissue of origin, which involves identifying the specific type of cell or tissue from which the tumor arose. This classification helps pathologists determine the biological behavior and characteristics of the neoplasm. While the distinction of benign versus malignant is important, it is not the primary method of classification.

Benign and malignant designations do indicate the potential for invasion and metastasis, which is crucial in the clinical management of neoplasms. However, understanding the tissue of origin provides a foundation for diagnosing specific types of tumors and directing treatment. This tissue-based classification encompasses various categories such as carcinomas (epithelial origin), sarcomas (connective tissue origin), lymphomas (lymphatic tissue origin), and others, establishing a framework for further investigation into the neoplasm's behavior and prognosis.

Other options, such as size and location or genetic mutations, can be relevant in characterizing neoplasms but do not serve as the primary classification method in pathology. Understanding tissue of origin remains paramount in the identification and classification process.